Using this bag is super easy. Unzip the compartments and start filling them with your toiletries, makeup, pencils, or whatever you want to organize. For toiletries, put your toothbrush and toothpaste in one of the smaller compartments, and your hairbrush in another. If you're using it for school supplies, pens can go in one and pencils in another. When it comes to maintenance, since it's easy to clean inside and out, just use a mild soap and a damp cloth to wipe it down regularly. Avoid overloading it beyond the 15 - lb capacity as it may damage the bag. Keep it in a dry place when not in use to ensure its longevity.